Single particle tracking of alpha7 nicotinic AChR in hippocampal neurons reveals regulated confinement at glutamatergic and GABAergic perisynaptic sites.

This effect was accompanied by a highly significant increase in mobility of α7-nAChRs residing on dendrites (from 0.018±0.024 to 0.025±0.027 μm 2 /s; t = 5.015 df = 1352, p = 0.0023) whereas axonal QDs exhibited a moderate reduction in mobility (from 0.218±0.104 to 0.187±0.04 μm 2 /s; t = 2.811 df = 289, p = 0.0103) ( Fig. 6A ).

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