The challenge of metastatic colorectal cancer.

Clin Med Insights Oncol · 2010 · PMC2902204 · PMID 20711244

Europe PMC DOI

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an overall trendno p-value reported

Of the 15 patients with PIK3CA mutations, none demonstrated an objective tumor response to EGFR inhibitor therapy, and an overall trend of decreased PFS was observed.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.