Similarly, the median level of rigidity of erythrocytes infected with FIKK12-KO parasites was also lower than those infected with FCR3 but the difference did not quite reach statistical significance at the 95% confidence level (P = 0.06) These suggest that both FIKK7.1 and FIKK12 play a role in modulating the overall level of membrane rigidification induced by P. falciparum infection.
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Plasmodium falciparum FIKK kinase members target distinct components of the erythrocyte membrane.
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