Inhibitory effects of ZSTK474, a novel phosphoinositide 3-kinase inhibitor, on osteoclasts and collagen-induced arthritis in mice.

Arthritis Res Ther · 2010 · PMC2911876 · PMID 20482767

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highly significantno p-value reported

At Day 52, there were highly significant differences between the vehicle-treated group and the ZSTK474 (100 mg/kg)-treated group (mean arthritis score: 6.8 ± 1.0 versus 2.4 ± 0.5, Figure 4c ).

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