Genome-wide analysis reveals novel genes essential for heme homeostasis in Caenorhabditis elegans.

Highly significant GO terms ( P <0.005) associated with the subset of genes that were upregulated at 4 μM heme were ‘embryonic development’, ‘lipid transport’, and ‘proteolysis’ ( Figure 4C ; Table S6 ); ‘responses to stress’ and environmental stimuli' were associated with genes that were downregulated at 4 μM heme ( Figure S2 and Tables S7 , S8 , S9 ).

also in 132,142 other papers