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HIV-1 Populations in Semen Arise through Multiple Mechanisms.

PLoS Pathog · 2010 · PMC2924360 · PMID 20808902

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an increasing trendno p-value reported
This may reflect an increasing trend to fail to control viral replication but with a continued response to the presence of viral antigen.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.