Deletion of LCE3C and LCE3B genes at PSORS4 does not contribute to susceptibility to psoriatic arthritis in German patients.

The lack of association is most probably not due to the geographical origin of the patients, as we identified highly significant association to the deletion in an independent study of patients with PsV without joint manifestation retrieved from the same population (Germany) 22 similar in magnitude to that recently reported. 19 Likewise, we did not observe evidence for association in the subset of 502 patients with PsA with manifestation ≤40 years of age (type I psoriasis) and average age of onset in the subset was comparable to the one of the above mentioned PsV cohort ((24.0±9.5 and 23.2±11.9, respectively).

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