Prolonged Abeta treatment leads to impairment in the ability of primary cortical neurons to maintain K+ and Ca2+ homeostasis.

At the same time steady-state values of Ca 2+ fluxes measured 20 min after the glutamate challenge were not statistically different from the relevant values of age-similar control cells even after six and eight days of Aβ treatment, despite an apparent trend towards an increase in Ca 2+ flux values (Figure 7B ).

also in 709 other papers