The proneural molecular signature is enriched in oligodendrogliomas and predicts improved survival among diffuse gliomas.

It is worth noting that the PN-Oligo samples had highly significant frequency of co-deletion of chromosomes 1p36 and 19q13.

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We reanalyzed the survival data excluding these two cases (HF1150 and HF0510), and none of the statistical findings were affected, except that the p-value for HR comparing classic and proneural oligodendrogliomas increased to 0.0595 (marginally significant) from 0.0100 (significant), which is not too surprising given that the sample size of the oligodendrogliomas was reduced by two.

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