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A senescence-like cell-cycle arrest occurs during megakaryocytic maturation: implications for physiological and pathological megakaryocytic proliferation.

PLoS Biol · 2010 · PMC2935456 · PMID 20838657

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highly significantno p-value reported
This enrichment was highly significant for up-regulated genes.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.