Incremental genetic perturbations to MCM2-7 expression and subcellular distribution reveal exquisite sensitivity of mice to DNA replication stress.

PLoS Genet · 2010 · PMC2936539 · PMID 20838603

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highly significantno p-value reported

In the case of Mcm2 , there was a striking and highly significant shortfall of Mcm4 Chaos3/Chaos3 Mcm2 Gt/+ offspring at birth ( Figure 3A ; Figure S2 ).

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