Barely Significant
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Disease-modifying therapies in relapsing-remitting multiple sclerosis.

Neuropsychiatr Dis Treat · 2010 · PMC2938285 · PMID 20856600

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a nonsignificant trendno p-value reported
26 Methotrexate The only study of methotrexate in progressive MS revealed a nonsignificant trend in sustained reduction of disease progression on the Expanded Disability Status Scale and number of relapses in favor of methotrexate.

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