A biopsy sample reduction approach to identify significant alterations of the testicular transcriptome in the presence of Y-chromosomal microdeletions that are independent of germ cell composition.

Hum Genet · 2010 · PMC2939328 · PMID 20668881

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highly significantp = 2E−14actually significant

We subjected the top 200 variant genes to GO (gene ontology) term analysis and found a highly significant over-representation of terms such as spermatogenesis ( p = 2E−14), mitosis ( p = 5E−6) and meiosis ( p = 1E−3).

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