Barely Significant
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Amino acid composition in endothermic vertebrates is biased in the same direction as in thermophilic prokaryotes.

BMC Evol Biol · 2010 · PMC2939578 · PMID 20807394

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highly significantp < 10 -15actually significant
Analysing the combined amino acid composition of the complete proteomes, we indeed find a small but statistically highly significant shift in ERK of endothermic compared to ectothermic vertebrates (Figure 3 ; Wilcoxon rank sum test: p < 10 -15 ).

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