Epidemiological study of phylogenetic transmission clusters in a local HIV-1 epidemic reveals distinct differences between subtype B and non-B infections.

Multivariate analysis assigned a significant predictive value of homosexual transmission to infection with a subtype B virus (p < 0.001), Caucasian origin (p = 0.002), past or present syphilis infection (p < 0.001), being part of a transmission cluster (p = 0.004), past or present HBV (p = 0.012), and, with borderline significance, infection with a drug resistant virus (p = 0.05) (Table 3 ).

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