Global mapping of binding sites for Nrf2 identifies novel targets in cell survival response through ChIP-Seq profiling and network analysis.

This finding of 50% sensitivity (considering only the peaks that strictly overlap a site) is highly significant (Fisher’s exact test; P < 2.2 e –16) and is a strong indication of the quality of the results, all the more so as the literature derived studies were performed in a variety of species and cell types.

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