Trait-stratified genome-wide association study identifies novel and diverse genetic associations with serologic and cytokine phenotypes in systemic lupus erythematosus.

Instead, there was a highly significant relationship between serum IFN-α and LRRC20 genotype in a joint analysis of European- and Hispanic-American subjects ( P = 2.1 × 10 -4 ), in whom the serologic association with anti-La antibodies was not present (Supplemental figure S2 in Additional file 1 ).

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