The high cephalic spread of ropivacaine analgesia may be significant but still its quality may not correlate with the level of sensory analgesia.[ 13 ] The addition of clonidine as an adjuvant allows a lesser dose of ropivacaine when used intrathecally for cesarean section.[ 14 ] Clonidine augments the action of local anesthetics in regional blockades by interrupting the neural transmission of painful stimuli in Aδ and C fibres as well as augments the blockade of local anesthetic agents by increasing the conductance of K + ions in nerve fibres.
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Comparison of epidural ropivacaine and ropivacaine clonidine combination for elective cesarean sections.
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