Among the three analysis models (codominant, dominant, and recessive models), the ADRB2, Arg16Gly, Leu134Leu, and Arg173Arg polymorphisms showed highly significant effects on the prevalence of serum specific IgE to the TDI-HSA conjugate, with the highest significance observed in the codominant model (OR, 3.09; 95% CI, 1.47-6.51 for Arg16Arg A>G, OR, 2.42; 95% CI, 1.16-5.07 for Leu134Leu G>A and OR, 2.97; 95% CI, 1.39-6.32 for Arg173Arg C>A) ( Table 3 ).
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Probable role of Beta 2-adrenergic receptor gene haplotype in toluene diisocyanate-induced asthma.
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