We observed a slight trend toward increased infectivity in Mfge8 −/− brains (7.48 ± 0.07 TCI [infectious tissue culture] units and 7.30 ± 0.12 TCI units in Mfge8 +/+ and Mfge8 −/− brains, respectively), which, however, did not attain statistical significance (Fig.
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Engulfment of cerebral apoptotic bodies controls the course of prion disease in a mouse strain-dependent manner.
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