highly significantp < 0.0001
The change in localization between unbudded and small-budded cells was highly significant (using a two-tailed t test, p < 0.0001 for INO1 ; p = 0.0047 for GAL1 ), as was the change between small- and large-budded cells (p = 0.003 for INO1 ; p = 0.005 for GAL1 ).