Glucokinase activators (GKAs) promise a new pharmacotherapy for diabetics.

F1000 Med Rep · 2010 · PMC2950051 · PMID 20948841

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may be significantno p-value reported

Impaired formation of a GK/BAD complex proposed to associate with mitochondria and to enhance glucose oxidation may be significant for the molecular pathogenesis of the functional beta-cell defect and apoptotic beta-cell loss known to cause T2DM.

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