Dynamic determinants of longevity and exceptional health.

The initial value of an index at age 40 (“ I n t e r c e p t 40−60 ”) is also a highly significant ( P < .0001) risk factor for mortality for HC and PP (i.e., higher values of respective index at age 40 correspond to higher risk of death compared to smaller values of this index), being nonsignificant for BG.

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In all cases (except for the right slope of PR which appeared either marginally significant or nonsignificant in the other studies), risk factors for which the estimates of the regression parameters were significant ( P < .01) in the original study exhibited similar significant effects on mortality risk or risk of onset of “unhealthy life” in other studies.

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