Balancing selection maintains a form of ERAP2 that undergoes nonsense-mediated decay and affects antigen presentation.

PLoS Genet · 2010 · PMC2954825 · PMID 20976248

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marginally non-significantno p-value reported

The excess of polymorphism is significant in two populations (Palestinian and Gujarati) and marginally non-significant in the Toscani group (HKA test [39] , Table 1 ), but fails to reach significance in the other populations (likely due to the limited power of the short coding regions).

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