ETV1 is a lineage survival factor that cooperates with KIT in gastrointestinal stromal tumours.

Nature · 2010 · PMC2955195 · PMID 20927104

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highly significantno p-value reported

Consistent with this KIT-MEK-ETV1 signalling pathway model, the overlap between genes transcriptionally altered by imatinib treatment (KIT-regulated) and by ETV1 knockdown in GIST882 cells is highly significant ( Fig. 4c ).

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