Synphilin-1 enhances α-synuclein aggregation in yeast and contributes to cellular stress and cell death in a Sir2-dependent manner.

PLoS One · 2010 · PMC2965147 · PMID 21060871

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highly significantno p-value reported

Nevertheless, the difference in survival and ROS production between wild-type cells with or without SY WT expression was still highly significant throughout the course of the experiment ( Fig. 7B,C ).

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