Region-specific genetic alterations in the aging hippocampus: implications for cognitive aging.

Front Aging Neurosci · 2010 · PMC2967426 · PMID 21048902

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highly significantno p-value reported

The Ingenuity Pathway analysis identified amyloid precursor protein signaling and the potassium channel signaling pathways as highly significant and downregulated in AU animals.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.