Genome-wide and follow-up studies identify CEP68 gene variants associated with risk of aspirin-intolerant asthma.

PLoS One · 2010 · PMC2972220 · PMID 21072201

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highly significantP = 6.0×10 −5actually significant

All seven SNPs of the CEP68 gene showed linkage disequilibrium (LD), and the haplotype of CEP68_ht4 (T-G-A-A-A-C-G) showed a highly significant association with aspirin intolerance (OR = 2.63; 95% CI = 1.64–4.21; P = 6.0×10 −5 ).

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