Genomic runs of homozygosity record population history and consanguinity.

PLoS One · 2010 · PMC2981575 · PMID 21085596

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closest p · 0.0× alpha

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highly significantp ≤0.0001actually significant

Pedigree-based estimates of the mean inbreeding coefficient, F ped , are available for 17 of the 51 populations and show highly significant and strong correlations with the very long ROH observed, peaking for the sum of ROH >10 Mb ( r = 0.87, p ≤0.0001).

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