Barely Significant
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Metallothioneins are required for formation of cross-adaptation response to neurobehavioral toxicity from lead and mercury exposure in nematodes.

PLoS One · 2010 · PMC2987793 · PMID 21124968

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highly significantno p-value reported
(1995) investigated the relationship between increased thermotolerance and life-span by developing conditions for environmental induction of thermotolerance, and found that the pretreatment at sub-lethal temperature induces increased thermotolerance and small but statistically highly significant increase in life expectancy [9] .

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.