Genome-wide association study identifies two novel regions at 11p15.5-p13 and 1p31 with major impact on acute-phase serum amyloid A.

PLoS Genet · 2010 · PMC2987930 · PMID 21124955

Europe PMC DOI

hedged sentence

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closest p · 0.0× alpha

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boldest claim

The sentences

borderline significantp = 2.76×10 −8actually significant

When the analysis was stratified by gender, one additional SNP (rs549485) located about 350 kb apart from the SAA1 subregion at 11p14 in the secretion regulating guanine nucleotide exchange factor ( SERGEF ) gene showed a borderline significant association with A-SAA levels in men (p = 2.76×10 −8 ) in the meta-analysis.

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