Efficacy and acceptability of amineptine in Indian depressive patients : an open trial.

recordings did not reveal any abnor- mality. DISCUSSION This open study involved 40 patients with major depressions, bipolar disorders and dysthymic disorders according to DSM III criteria. From the start of therapy with aminep- tine the mood level of the included patients showed a positive trend, the antidepressant effect of amineptine reached significance after two weeks therapy in the Hamilton Rating Scale of Depression nrtd after four weeks in the Clinical Global Evaluation.

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