Appetitive operant conditioning in mice: heritability and dissociability of training stages.

Even with low variability – high heritability traits such as morphometric data on brain area size, QTLs may not be detected due to a relatively small contributing effect of each individual QTL (Crusio, 2004 ) which often results in difficulties finding highly significant QTLs for complex traits.

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In contrast, the partial correlations between nose poke and lever press–nose poke performance ( r = 0.29, p = 0.09828; with initial magazine checking partialed out) and initial magazine checking and lever press–nose poke performance ( r = 0.31, p = 0.07664; with reward collection partialed out) showed a slight trend toward correlation but were insignificant.

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