Highly significant enrichment was identified for encoded proteins involved in cell-to-cell communication and signal transduction (DCBLD2, IL15, ITGA2, ITGA6, ITGA11, NPR3, RAPGEF2, SPRY2, STMN2) (p=0.036), with nine of the proteins integral to the plasma membrane (DCBLD2, IL15, ITGA2, ITGA6, ITGA11, PODXL, RAPGEF2, SHROOM3, THBD) (p=0.0032).
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Scalp fibroblasts have a shared expression profile in monogenic craniosynostosis.
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