Polyamines are present in mast cell secretory granules and are important for granule homeostasis.

PLoS One · 2010 · PMC2994821 · PMID 21151498

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a mild trendno p-value reported

5C and 5D , mMCP-6 and mMC-CPA protein levels showed only a mild trend to increase after the DFMO treatment.

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a slight trendno p-value reported

In support of this hypothesis, histamine synthesis rate showed a slight trend to increase after the DFMO treatment, although not statistically significant (HDC enzymatic activity in pmol/h/10 6 cells: control 8.31±1,76 versus DFMO 12.8±1.3; P = 0.24).

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