showed that the duration of the first sleep period was prolonged by 108 min (placebo group: 41 min, P <0.001) and an average of >5 hr of unbroken first sleep period per night was experienced by 27% of desmopressin-treated patients (placebo group: 9%), resulting in a highly significant between-group difference ( 25 ).
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Desmopressin is an effective treatment for mixed nocturia with nocturnal polyuria and decreased nocturnal bladder capacity.
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