Barely Significant
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Polymorphisms of the ITGAM gene confer higher risk of discoid cutaneous than of systemic lupus erythematosus.

PLoS One · 2010 · PMC2996302 · PMID 21151989

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hedged sentence
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The sentences

highly significantP -value = 4.73×10 −11actually significant
Analysis of the ITGAM coding variant rs1143679 showed highly significant association to DLE in patients without signs of systemic disease ( P -value = 4.73×10 −11 , OR = 3.20, 95% CI = 2.23–4.57).

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