Barely Significant
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Systematic analysis of off-target effects in an RNAi screen reveals microRNAs affecting sensitivity to TRAIL-induced apoptosis.

BMC Genomics · 2010 · PMC2996961 · PMID 20230625

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0.0002
closest p · 0.0× alpha
0.0002
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highly significantP < 0.0002actually significant
Although observing two siRNA sharing a hexamer seed sequence is not significant at the 5% level, observing two or more such seeds is significant (P = 0.013), while finding four siRNAs sharing a seed sequence is highly significant (P < 0.0002).

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