Genetic variants in the TIRAP gene are associated with increased risk of sepsis-associated acute lung injury.

BMC Med Genet · 2010 · PMC3001691 · PMID 21118491

Europe PMC DOI

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highly significantP = 0.00006actually significant

Associations of the TIRAP gene haplotypes with ALI risk We next carried out haplotype analysis on the basis of these two associated SNPs and found that a two-allele model of risk provided the strongest predictor of risk, which was highly significant (P = 0.00006 in ALI group vs control group and P = 0.00003 in ALI group vs sepsis alone group).

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