Type 1 plasminogen activator inhibitor (PAI-1) in clear cell renal cell carcinoma (CCRCC) and its impact on angiogenesis, progression and patient survival after radical nephrectomy.

Even though there were very few PAI-1 positive tumours in organ confined stages (T1/T2), this molecular marker turned out to be a highly significant predictor of developing metachronous metastasis in these patients with HR = 13,71 (p = 0.002).

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