Barely Significant
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Melatonin and its agonist ramelteon in Alzheimer's disease: possible therapeutic value.

Int J Alzheimers Dis · 2010 · PMC3004402 · PMID 21197086

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a nonsignificant trendno p-value reported
In a large multicentre trial only a nonsignificant trend to improvement in the circadian rhythm disturbance of AD is when treatment was done using melatonin [ 120 ].

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