A large-scale meta-analysis to refine colorectal cancer risk estimates associated with MUTYH variants.

Br J Cancer · 2010 · PMC3008602 · PMID 21063410

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marginally significantno p-value reported

A marginal significant mono-allelic effect was demonstrated for the specific variant Y179C (OR=1.34 (95% CI: 1.00–1.80)) and indeed a marginally significant result was also observed in the pooled meta-analysis for MUTYH WM (OR=1.16 (95% CI: 1.00–1.34)) and Y179C variant alone, 1.34 (95% CI: 1.01–1.77).

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