Loss of glutathione peroxidase 3 expression is correlated with epigenetic mechanisms in endometrial adenocarcinoma.

The majority of the rat tumors displayed an almost total loss of expression of Gpx3 whereas the non-/pre-malignant endometrial samples displayed a normal/high expression, as also shown by the highly significant difference among malignant and premalignant/normal samples, (p < 0.001, Figure 1 , Table 1 ).

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