Physicochemical properties of pore residues predict activation gating of Ca V1.2: a correlation mutation analysis.

Pflugers Arch · 2011 · PMC3016219 · PMID 20924598

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highly significantno p-value reported

No improvement was observed for any combined descriptor correlation (Table 3 ). Modulation of hydrophobic interactions in I781 (IIS6) by other amino acid properties In a previous study, we found a highly significant correlation between changes in hydrophobicity (Δ H ) and Δ V act for mutations in position I781 of segment IIS6 [ 17 ].

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