borderline significanceP = 0.05
These significant findings persisted after adjustment of age for the association between obesity and methylation status of the CpG site in the UBASH3A gene ( P = 0.008) and TRIM3 gene ( P = 0.001), but changed to borderline significance for HIPK3 gene ( P = 0.05), and disappeared for the CpG site in the CDH5 gene ( P = 0.095).