marginally significantP = 0.106
In the GBM model 3 with 5 stem cell associated gene expressions, a marginally significant improvement was seen in the prognosis model (R 2 = 11.2%, P = 0.106).
In the GBM model 3 with 5 stem cell associated gene expressions, a marginally significant improvement was seen in the prognosis model (R 2 = 11.2%, P = 0.106).
Kaplan-Meier survival analysis was performed for a highly significant prognosis factor MSI1 dichotomized at the overall median expression in a total of 194 glioma samples including GBM, AA, and AO_O.
The addition of the 8 cancer pathway related genes ( CDK4 , EGFR, MMP2 , VEGFA , PAX6 , PTEN , RPS9 , and IGFBP2 ) or the 5 stem cell associated genes, improved the R 2 of the AA model (AA Model 2, R 2 = 32.7% and AA model 3, R 2 = 22.0%) with marginal significance on the likelihood ratio test.