Barely Significant
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An unexpected cause of deranged liver function: pyogenic liver abscess.

JRSM Short Rep · 2011 · PMC3031185 · PMID 21286227

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an increasing trendno p-value reported
Discussion Pyogenic liver abscess is a rare condition, with a hospital incidence between 2–18 per 100,000 population, and suggestion of an increasing trend in incidence. 1 – 3 In the pre-antibiotic era, pyogenic liver abscesses occurred in young patients around their third to fourth decade due to intra-abdominal infections, commonly secondary to appendicitis. 4 Now, the median age is in the sixth decade, and biliary tract disease is the commonest source of infection. 1 , 5 , 6 This includes cholecystitis, gallstones, cholangiocarcinoma and pancreatic tumour.

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