Ulcerative colitis and Crohn's disease: is Mycobacterium avium subspecies paratuberculosis the common villain?

In HC subjects, clearance rates were relatively stable between 10 5 and 3 × 10 7 organisms and actually increased at the highest dose, whereas in CD, although it was normal at 10 5 and 10 6 , there was a dramatic and highly significant drop in clearance at and above 10 7 bacteria [ 73 ].

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