Gene expression profiling of rat spermatogonia and Sertoli cells reveals signaling pathways from stem cells to niche and testicular cancer cells to surrounding stroma.

BMC Genomics · 2011 · PMC3033334 · PMID 21232125

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Published gene expression profiles of testis cancer showed a highly significant overlap with gene sets over-expressed in pre-pubertal Spga and Sertoli cells underlining the relevance of the SSC to niche communication in the development of testis cancer.

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