Chromosome 11q13.5 variant associated with childhood eczema: an effect supplementary to filaggrin mutations.

5 FLG remains the most highly significant and widely replicated genetic risk factor for atopic eczema, with an estimated odds ratio (OR) of 3.12. 6 However, even in the most severe case series, a maximum of 50% of cases carry FLG null alleles. 7 The first genome-wide association study in atopic eczema has recently identified a novel suscep

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